Generic Aygestine is used to prevent abnormal uterine bleeding due to hormonal imbalance or to restore menstrual periods.
To prevent abnormal uterine bleeding due to hormonal imbalance or to restore menstrual periods:
- The usual dose is 2.5 to 10 milligrams a day taken for 5 to 10 days during the second half of a 28-day cycle. Your period should start 3 to 7 days after you stop taking norethindrone.
To treat endometriosis:
- The recommended starting dose is 5 milligrams a day for 2 weeks. The doctor may increase your dose by 2.5 milligrams a day every 2 weeks up to a maximum of 15 milligrams a day. Treatment may continue for 6 to 9 months or until intolerable breakthrough bleeding occurs.
All progesterone drugs are associated with certain side effects, none of which can be anticipated. If any side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine whether it is safe for you to continue taking norethindrone.
Side effects caused by progesterone drugs may include: acne, allergic reaction, blood clots in the arteries, veins, eyes, or lungs, breakthrough menstrual bleeding, breast enlargement or tenderness, bulging eye, depression, double vision, cervical changes or secretions, change in menstrual flow, headache, hives, inflammation of the optic nerve, insomnia, menstrual spotting, migraine, mood swings, nausea, rash with or without itchy spots, skin discoloration, stopping of menstrual flow, swelling, vision loss, weight increase or decrease, yellowing of the skin or eyes
Side effects caused by estrogen/progesterone combinations may include: appetite changes, backache, blood pressure increase, bull's-eye rash, changes in appetite, changes in sex drive, dizziness, fatigue, hair growth or loss, headache, inflammation of the urinary tract, itching, nervousness, skin bruising, symptoms similar to premenstrual syndrome, red or tender skin nodules.
Norethindrone may cause some degree of fluid retention. If you have a medical condition that could be made worse by fluid retention--such as epilepsy, migraine, asthma, or a heart or kidney problem--make sure your doctor knows about it.
Be sure to tell your doctor if you experience any irregular or unexplained vaginal bleeding while taking norethindrone.
Norethindrone makes some women depressed. If you've suffered from serious depression in the past, alert your doctor if you think you're having a relapse. You will probably need to stop taking norethindrone.
Norethindrone may affect cholesterol and blood-sugar levels. If you have diabetes or high cholesterol, your doctor will want to watch you closely while you are taking norethindrone.
If norethindrone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Make sure your doctor knows about all the prescription and over-the-counter drugs you are taking.
In general, when you are taking a progesterone drug such as norethindrone, it is especially important to check with your doctor before taking the following:
- Aminoglutethimide (Cytadren)
- Carbamazepine (Tegretol)
- Phenytoin (Dilantin)
- Rifabutin (Mycobutin)
- Rifampin (Rifadin, Rimactane)
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.
Store at room temperature in a tightly closed container.